Researchers from London's Imperial College Centre for Synthetic Biology & Innovation
created a new DNA assembly method that is fast, accurate, modular, works exactly the same way
in every tier of hierarchical assemblies and can be completely automated.
The BASIC DNA assembly method uses linkers to assemble DNA bioparts
stored in BASIC format in a user specified order.
Step 1: half-sections of linkers are ligated onto the bioparts
Step 2: unligated linkers are removed via magnetic bead purification
Step 3: purified parts are combined into final assembly and transformed
What do you need to get started?
Get BASIC bioparts that are ready to use and create your own BASIC parts
Get BASIC linker sets from Biolegio - high quality and affordable in a user friendly format
Get Magnetic Beads from Nimagen - Ampliclean beads are affordable and reliable
Use the BASIC protocol for simple DNA assembly at bench scale
Use the BASIC app to design your constructs and workflows
Coming soon: Use automated BASIC on the Opentrons OT-2